Our site has extensive experience in conducting
clinical trials in the following areas:
To learn more about
recruiting studies, Please contact us at
203-754-3588 or e-mail us at
ccrcinfo@ctclinicalresearchcenter.com
To learn more about some of the studies and
research terminology you may visit the following
websites:
http://www.centerwatch.com/patient/glossary.html
http://clinicaltrials.gov/
Benign Prostatic Hyperplasia (BPH)
Benign prostatic hyperplasia (BPH) also
is called enlarged prostate. BPH is a
non-cancerous enlargement of the prostate gland.
Changing hormone levels occurring with age
causes BPH. This often occurs around the age of
50. Excess tissue can block the urethra, causing
various symptoms such as:
-
Difficulty urinating
-
The enlarged prostate can also press on the
bladder, so you may need to urinate more
often
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Straining during urination
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A weak urine stream
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Feeling that the bladder isn’t emptying all
the way
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Bladder Cancer
Bladder cancer usually originates in
the bladder lining, which consists of a mucous
layer of surface cells. Tumors are categorized
as low-stage (superficial) or high-stage (muscle
invasive). More than 90% of cases originate in
the transitional epithelial cells (transitional cell carcinoma).
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Erectile Dysfunction (ED)
Erectile dysfunction (ED) is also
called impotence. Erectile dysfunction (ED) is
the inability of a man to achieve or maintain an
erection sufficient for his sexual needs or the
needs of his partner. Many men experience this
at some point in their lives. Some men,
experience chronic, complete erectile
dysfunction (impotence), and others, partial or
brief erections. Frequent erectile dysfunction
can cause emotional and relationship problems,
and often leads to diminished self-esteem.
Erectile dysfunction has many causes, most of
which are treatable, and is not an inevitable
consequence of aging.
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Female Sexual Dysfunction (FSD)
FSD may be classified under one or more
categories including Desire, Arousal, Orgasmic
and Pain Disorders. The common causes of FSD are
decreased blood supply to the clitoris,
complications of nerve or spinal cord surgery,
or consequences of chronic medical conditions or
medications
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Hypogonadism
Hypogonadism is also known as Testosterone
Deficiency. Testosterone production declines
naturally with age. Low testosterone, may result
from disease or damage to the hypothalamus,
pituitary gland, or testicles that inhibit
hormone secretion and testosterone production.
Depending on age, insufficient testosterone
production can lead to abnormalities in muscle
and bone development, and diminished libido and
depression.
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Incontinence
Incontinence is the loss of voluntary
control over urinary functions. There are
many types of urinary incontinence:
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Stress
Losing urine involuntarily during certain
physical activities: coughing, laughing or
sneezing; lifting; walking or performing
other forms of exercise; moving to get up
from a chair or out of bed.
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Urge
Inability to control the sudden urge to
urinate. A large amount of urine may be
released. Urge incontinence may occur after
a sudden change in position or activity.
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Mixed
A mixture of stress and urge incontinence.
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Interstitial Cystitis (IC)
Interstitial cystitis (IC) is a chronic
inflammatory condition of the bladder that
can cause frequent, urgent, and painful urination
with or without pelvic discomfort.
Women with IC typically complain of pain or
pressure in the pelvic area, pain during or
after sex, and frequent, sometimes painful,
urination. In addition,
women with IC are typically diagnosed with urinary tract infections.
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Over Active Bladder (OAB)
In people with an overactive bladder
(OAB), the detrusor muscle (bladder muscle)
contracts spastically, sometimes without a known
cause, which results in sustained, high bladder
pressure and the urgent need to urinate (called
urgency). Everyone is different, but the most
common signs of overactive bladder are a sudden
urgency, frequency and leakage.
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Peyronie’s
Disease (PD)
Peyronie's disease is characterized by the
formation of hardened tissue (fibrosis) in the
penis that can cause pain, curvature, and
distortion during erection. The penis
is composed of two columns of erectile tissue
(the corpora cavernosa) and the corpus spongiosum,
which contains the tube that carries urine and
semen from the body (urethra). In PD, a scar
(plaque) forms on the sheath surrounding the
corpora cavernosa.
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Premature Ejaculation (PE)
Premature ejaculation (PE) is a term used to
describe a condition in which a man regularly
ejects semen (i.e., ejaculates) soon after
the onset of sexual arousal, or sooner than he
or his partner wishes. This condition, which is
also called rapid ejaculation, is the most
common type of sexual dysfunction in men under
the age of 40.
Premature ejaculation can be primary
(in men who have had the condition since
puberty), or secondary
(acquired; in men who previously had control of
ejaculation). It may develop in men who have ED
and are anxious about maintaining an erection
during sexual intercourse.
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Prostate
Cancer
Adenocarcinoma of the prostate is the clinical
term for a cancerous tumor on the prostate
gland. As prostate cancer grows, it may spread
to distant
parts of the body (e.g., bones, liver).
Prostate cancer confined to the gland often is
treated successfully. Most Men with prostate
cancer can enjoy a long relatively healthy life.
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Prostatitis
Prostatitis is also known as Chronic Pelvic Pain
in men. Prostatitis is a term used to describe
inflammatory conditions of the prostate gland.
It is thought that most cases of prostatitis
result from bacterial infection, but evidence of
infection is not always found. An infected or
inflamed prostate can cause painful urination
and ejaculation, urinary frequency and urgency,
and if left untreated, chronic, recurrent
symptoms.
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Sperm
Assessments
This is usually done in the course of a
fertility evaluation, or to determine if sperm
are absent following a vasectomy. Research
studies are usually done to evaluate if a study
drug has any effect on sperm.
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Urinary
Tract Infection (UTI)
Urinary tract infection (UTI) is a
common infection that usually occurs when
bacteria enter the urethra and multiply in the
urinary tract. The urinary tract includes the
kidneys, the tubes that carry urine from the
kidneys to the bladder (ureters), bladder, and
the tube that carries urine from the bladder
(urethra). Men, women, and children develop
UTIs.
Urinary tract infections usually develop first
in the lower urinary tract (urethra, bladder)
and, if not treated, can progress to the upper
urinary tract (ureters, kidneys). Bladder
infection (cystitis) is by far the most common
UTI. Kidney infection (pyelonephritis) requires
urgent treatment and can lead to reduced kidney
function if left untreated.
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